BMJ · 1973 · 272 citations · 9 references
MedicineOrthopaedic SurgeryOrthopedic SurgeryBone MetabolismJoint Replacement SurgeryOrthopedicsBone HealthCobalt ToxicityHip ArthroplastyJoint Replacement MaterialsMetal ToxicityMetallic BiomaterialsBlood Chromium LevelsBlood Cobalt LevelsChromium AccumulationCobalt-chromium AlloysLong-term Exposure EffectsMetal Wear DebrisUrinary Cobalt LevelsWear
Raised levels of cobalt and chromium are found in the blood and urine of patients with metallic total hip replacements. When one of the hip components is made of polyethylene much less metal seems to be released from the joint. The long-term effects of the accumulation of chromium in the body need to be studied further.
9
The Journal of Investigative Dermatology
Naomi M. Kanof · Archives of Dermatology · 1967 · 1.4K citations
Henry A. Schroeder, Alexis P. Nason · PubMed · 1969 · 167 citations
Pharmacy, Chemistry, Toxicology +12