Anti‐IL‐5 recombinant humanized monoclonal antibody (Mepolizumab) for the treatment of atopic dermatitis - Concepedia

Concepedia

Publication | Closed Access

Anti‐IL‐5 recombinant humanized monoclonal antibody (Mepolizumab) for the treatment of atopic dermatitis

329

Citations

23

References

2005

Year

J Oldhoff, Ulf Darsow, Thomas Werfel, K. Katzer, A. Wulf, J. Laifaoui, DirkJan Hijnen, Sabine G. Plötz, Edward F. Knol, Alexander Kapp,

Abstract

Two single doses of 750 mg mepolizumab did not result in clinical success in patients with AD, despite a significant decrease in peripheral blood eosinophils.

References

	Year	Citations
Diagnostic Features of Atopic Dermatitis Jon M. Hanifin, Georg Rajka Acta Dermato Venereologica Abstract AlgebraAllergyAtopic DermatitisAllergy MedicineHistopathology	1980	5.1K
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsìveness, and the late asthmatic response Margaret J Leckie, Anneke Ten Brinke, Jamey Khan, The Lancet AsthmaAllergyAllergy MedicineImmunologyAllergen	2000	1.8K
Clinical Validation and Guidelines for the SCORAD Index: Consensus Report of the European Task Force on Atopic Dermatitis B Kunz, A. P. Oranje, L. Labrèze, Dermatology	1997	1K
Interleukin-5, eosinophils, and disease CJ Sanderson Blood Primary ImmunodeficiencyInflammationAllergyImmunodeficienciesImmunology	1992	862
Eosinophil's Role Remains Uncertain as Anti–Interleukin-5 only Partially Depletes Numbers in Asthmatic Airway Patrick Flood-Page, Andrew Menzies‐Gow, A B Kay, American Journal of Respiratory and Critical Care Medicine	2003	804
Interleukin-5, eosinophils, and disease CJ Sanderson Blood	1992	784
Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo. Paul Collins, Sylvie Marleau, D A Griffiths-Johnson, The Journal of Experimental Medicine Intradermal InjectionEosinophil AccumulationImmune RegulationImmunologyEosinophilic Disorder	1995	652
Thymus and activation-regulated chemokine in atopic dermatitis: Serum thymus and activation-regulated chemokine level is closely related with disease activity Takashi Kakinuma, Koichiro Nakamura, Motoshi Wakugawa, Journal of Allergy and Clinical Immunology InflammationAtopic DermatitisSerum ThymusImmunologyImmune Regulation	2001	563
Roles of TH1 and TH2 cytokines in a murine model of allergic dermatitis Jonathan M. Spergel, Emiko Mizoguchi, Hans C. Oettgen, Journal of Clinical Investigation	1999	382
Anti–interleukin-5 (mepolizumab) therapy for hypereosinophilic syndromes Jennifer K. Garrett, Sean C. Jameson, Blythe Thomson, Journal of Allergy and Clinical Immunology	2004	363

Page 1