Airway inflammation and altered alveolar macrophage phenotype pattern after repeated low‐dose allergen exposure of atopic asthmatic subjects

Abstract

Repeated low-dose allergen exposure induces an allergic airway inflammation in asthmatic subjects. The inflammation is associated with an altered AM phenotype pattern, consistent with an influx of monocytes and a hypothetical increased accessory cell function in the airways, possibly contributing to the development and sustenance of airway inflammation in asthma.