Interferon-γ release assay for tuberculosis in patients with psoriasis treated with tumour necrosis factor antagonists:<i>in vivo</i>and<i>in vitro</i>analysis

Abstract

Fluctuations of IFN-γ release may occur in patients with psoriasis treated with TNF antagonists. The clinical use of repeated blood tests and the correct interpretation of individual IFN-γ changes could be useful in identifying possible cases of LTBI reactivation or newly acquired tuberculosis infection during long-term anti-TNF treatment.