Brain imaging: Applications in psychiatry

Abstract For more than a century psychiatrists have suspected neuropathology in patients with mental illness. In the last decade there have been developed several technologies that are capable of looking at both neuroanatomy and neurophysiology in the brains of living humans. First, x‐ray computerized axial tomography led the way in visualizing the living brain, and now magnetic resonance imaging allows brain structure to be shown with even more clarity. Brain electrical activity mapping allows computerized maps of electrophysiological activity to be visualized in a way never before possible. Nuclear medicine has provided the means of looking at various metabolic and neurochemical parameters in the living brain. These include regional cerebral blood flow studies using xenon 133 , single photon emission tomography, and positron emission tomography. Psychiatrists are cautiously optimistic that these various brain imaging technologies will be important new tools in continued exploration of the causes of mental illness and ultimately may lead to more effective treatments.