Nano Indium Oxide as a Recyclable Catalyst for C−S Cross-Coupling of Thiols with Aryl Halides under Ligand Free conditions

Abstract

An efficient ligand-free C-S cross-coupling of aryl halides with aromatic/alkyl thiols has been developed using a catalytic amount of nanocrystalline indium oxide as a recyclable catalyst with KOH as the base in DMSO at 135 degrees C. A variety of aryl sulfides can be synthesized in excellent yields utilizing this protocol.