Bulletin of the Chemical Society of Japan · 1983 · 39 citations · 0 references
Natural SciencesChemistryOrganic ChemistryOrganic SynthesisKetonesPerfluoroalkyl SubstancesPyridine Chemistry
Abstract The preparative method for dimethyl (trifluoromethyl)malonate (4) from the adduct of perfluoro-2-methylpropene with methanol was improved, and several reactions of this base-sensitive substance were investigated. Alkylation of 4 was achieved by using CsF as a condensing agent, and the Michael addition on vinyl ketones proceeded in triethylamine–pyridine medium.