Quantitative Measurements of Cardiac Phosphorus Metabolites in Coronary Artery Disease by ³¹ P Magnetic Resonance Spectroscopy

Abstract

Compared with healthy control subjects, PCr content decreased significantly in patients with both reversible and fixed 201Tl defects, and ATP content decreased significantly in subjects with fixed thallium defects. These results suggest that the measurement of ATP content in the human heart by 31P MRS is a clinically important method for the evaluation of myocardial viability.