Concepedia

Metal-free synthesis of imidazopyridine from nitroalkene and 2-aminopyridine in the presence of a catalytic amount of iodine and aqueous hydrogen peroxide

Yuma Tachikawa, Yoshitomo Nagasawa, Sohei Furuhashi, Lei Cui, Eiji Yamaguchi, Norihiro Tada, Tsuyoshi Miura, Akichika Itoh

RSC Advances · 2015 · 30 citations · 48 references

DOI

Concepts

Abstract

We have developed a metal-free synthetic method for 3-nitroimidazo[1,2-<italic>a</italic>]pyridines from nitroalkenes and 2-aminopyridines using catalytic amounts of iodine and aqueous hydrogen peroxide as a terminal oxidant.

References

48

Recent Developments in the Isonitrile‐Based Multicomponent Synthesis of Heterocycles

Jieping Zhu · European Journal of Organic Chemistry · 2003 · 943 citations · Full text

, , +14

A New Heterocyclic Multicomponent Reaction For the Combinatorial Synthesis of Fused 3-Aminoimidazoles

Hugues Bienaymé, Kamel Bouzid · Angewandte Chemie International Edition · 1998 · 426 citations

, , +11

Imidazo[1,2-<i>a</i>]pyridines Susceptible to Excited State Intramolecular Proton Transfer: One-Pot Synthesis via an Ortoleva–King Reaction

Anton J. Stasyuk, Marzena Banasiewicz, Michał K. Cyrański et al. · The Journal of Organic Chemistry · 2012 · 331 citations

, , +11

Copper‐Catalyzed Intramolecular Dehydrogenative Aminooxygenation: Direct Access to Formyl‐Substituted Aromatic N‐Heterocycles

Honggen Wang, Yong Wang, Dongdong Liang et al. · Angewandte Chemie International Edition · 2011 · 327 citations

, , +15

Derivatives of Imidazole. I. Synthesis and Reactions of Imidazo[1,2-α]pyridines with Analgesic, Antiinflammatory, Antipyretic, and Anticonvulsant Activity

L Almirante, Luigi Polo, A Mugnaini et al. · Journal of Medicinal Chemistry · 1965 · 308 citations

, , +13