Adeno‐associated virus vector‐mediated systemic interleukin‐10 expression ameliorates hypertensive organ damage in Dahl salt‐sensitive rats

Abstract

This is the first study to demonstrate that the anti-inflammatory cytokine IL-10 has a significant anti-hypertensive effect. AAV vector-mediated IL-10 expression potentially prevents the progression of refractory hypertension and hypertensive organ damage in humans.