Concepedia

Tissue- and time-dependent effects of endothelin-1 on insulin-stimulated glucose uptake11Abbreviations: 2-DOG, 2-deoxy-D-[3H]glucose; CI-150, dose of insulin required to increase 2-DOG uptake by 50% relative to control, 100%; DMEM, Dulbecco’s Modified Eagle Medium; ET-1, Endothelin-1; IRS, insulin receptor substrate; PI, phosphatidylinositide; PKC, protein kinase C; RT-PCR, reverse transcribed polymerase chain reaction.

Iskandar Idris, Divina Patiag, Samuel Gray, Richard Donnelly

Biochemical Pharmacology · 2001 · 17 citations · 15 references

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Concepts

References

15

Insulin stimulates endothelin-1 secretion from human endothelial cells and modulates its circulating levels in vivo.

Claudio Ferri, Valerio Pittoni, Alfonso Piccoli et al. · The Journal of Clinical Endocrinology & Metabolism · 1995 · 196 citations

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G Alpha-q/11 Protein Plays a Key Role in Insulin-Induced Glucose Transport in 3T3-L1 Adipocytes

Takeshi Imamura, Péter Vollenweider, Katsuya Egawa et al. · Molecular and Cellular Biology · 1999 · 182 citations

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Endothelin-1 modulates insulin signaling through phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells.

Zhen Jiang, Quan Zhou, Arpita Chatterjee et al. · Diabetes · 1999 · 125 citations

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Endothelin action in rat liver. Receptors, free Ca2+ oscillations, and activation of glycogenolysis.

C. Serradeil‐Le Gal, Catherine Jouneaux, A Sanchez-Bueno et al. · Journal of Clinical Investigation · 1991 · 110 citations · Full text

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Insulin stimulates endothelin binding and action on cultured vascular smooth muscle cells.

Harrison J.L. Frank, Ellis R. Levin, Ran Hu et al. · Endocrinology · 1993 · 102 citations

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