Interaction Between Host Gastric Sialyl-Lewis X and H. pylori SabA Enhances H. pylori Density in Patients Lacking Gastric Lewis B Antigen

Abstract

In Taiwan, H. pylori isolates are 100% BabA-positive, but only 31% of them express SabA. The interaction between gastric sialyl-Le(x) and SabA of H. pylori determines the colonization density of patients expressing gastric Le(b) weakly or not at all.