Ameliorative Effects of Baicalein on an Amyloid-βinduced Alzheimer’s Disease Rat Model: a Proteomics Study

Abstract

Baicalein ameliorates the Aβ1-40-induced dementia in rats and may be a novel and promising drug for the treatment of AD. The therapeutic mechanism may be related to modulation of a number of processes, mainly through the promotion of energy metabolism and neurotransmission, with the additional promotion of anti-apoptosis, anti-oxidation, protein phosphorylation, etc.