Can Methylphenidate Objectively Provide Relief in Patients With Uncontrolled Blepharospasm? A Pilot Study Using Surface Electromyography

Abstract

A significant decrease in mean voltage after the administration of Ritalin was found in this preselected group of patients. Subjective improvement with decreased disability and increased functional benefit was also found in all subjects. Based on the results of this study, a randomized, controlled study comparing Ritalin versus placebo is needed to determine whether Ritalin should be routinely prescribed for benign essential blepharospasm during the symptomatic window period.