Clinical, immunological and genetic features in Taiwanese patients with the phenotype of hyper-immunoglobulin E recurrent infection syndromes (HIES)

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

Guilian Niu, Kenneth L. Wright, Mei Huang et al. · Oncogene · 2002 · 1.2K citations

Medicine, Cancer Biology, Pathobiology +12

<i>STAT3</i> Mutations in the Hyper-IgE Syndrome

Steven M. Holland, Frank R. DeLeo, Houda Zghal Elloumi et al. · New England Journal of Medicine · 2007 · 1.2K citations · Full text

Life Sciences, Genetics, Immunology +13

Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome

Yoshiyuki Minegishi, Masako Saitō, Shigeru Tsuchiya et al. · Nature · 2007 · 1K citations

Life Sciences, Genetics, Immunology +13

Hyper-IgE Syndrome with Recurrent Infections — An Autosomal Dominant Multisystem Disorder

Bodo Grimbacher, Steven M. Holland, John I. Gallin et al. · New England Journal of Medicine · 1999 · 795 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

What does Stat3 do?

David E. Levy, Chien‐Kuo Lee · Journal of Clinical Investigation · 2002 · 738 citations

Natural Sciences, Bioinformatics, Statistics +2