A preparative synthesis of lapachol and related naphthoquinones

Beta-lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: a p53-independent response.

Sarah M. Planchon, Shelly M. Wuerzberger, Benjamín Frydman et al. · PubMed · 1995 · 205 citations · Full text

Medicine, Oncology, Pharmacology +17

Induction of DNA topoisomerase II-mediated DNA cleavage by beta-lapachone and related naphthoquinones.

Benjamín Frydman, L J Marton, Jian‐Sheng Sun et al. · PubMed · 1997 · 153 citations

Medicine, Molecular Biology, Pharmacology +12

Induction of apoptosis by beta-lapachone in human prostate cancer cells.

Chiang J. Li, Chao Wang, Arthur B. Pardee · PubMed · 1995 · 143 citations

Medicine, Oncology, Pharmacology +15

.beta.-Lapachone: synthesis of derivatives and activities in tumor models

K. SCHAFFNER‐SABBA, K. H. Schmidt-Ruppin, W. Wehrli et al. · Journal of Medicinal Chemistry · 1984 · 114 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

<i>In vitro</i>and<i>in vivo</i>evaluation of the toxicity of 1,4-naphthoquinone and 1,2-naphthoquinone derivatives against<i>Trypanosoma cruzi</i>

Jussara N. Lopes, Fernando S. Cruz, Roberto Docampo et al. · Annals of Tropical Medicine and Parasitology · 1978 · 112 citations

Medicine, Pharmacology, Toxicology +9