Concepedia

Blood gene expression markers to detect and distinguish target organ toxicity

Christina Umbright, Rajendran Sellamuthu, Shengqiao Li, Michael L. Kashon, Michael I. Luster, Pius Joseph

Molecular and Cellular Biochemistry · 2009 · 45 citations · 25 references

DOI

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References

25

The toxicity of acetaminophen and N-acetyl-p-benzoquinone imine in isolated hepatocytes is associated with thiol depletion and increased cytosolic Ca2+.

Matthew D. Moore, Hjördis Thor, Gregory Moore et al. · Journal of Biological Chemistry · 1985 · 411 citations · Full text

, , +17

Microarray analysis of hepatotoxins in vitro reveals a correlation between gene expression profiles and mechanisms of toxicity

Jeffrey F. Waring, Rita Ciurlionis, Robert A. Jolly et al. · Toxicology Letters · 2001 · 317 citations

, , +16

Identification of putative gene based markers of renal toxicity.

Rupesh P. Amin, Alison E.M. Vickers, Frank D. Sistare et al. · Environmental Health Perspectives · 2004 · 258 citations · Full text

, , +15

Gene Expression Profiling of Rat Livers Reveals Indicators of Potential Adverse Effects

Alexandra N. Heinloth, Richard D. Irwin, Gary A. Boorman et al. · Toxicological Sciences · 2004 · 203 citations · Full text

, , +16

Blood gene expression signatures predict exposure levels

Pierre R. Bushel, Alexandra N. Heinloth, J. Li et al. · Proceedings of the National Academy of Sciences · 2007 · 120 citations · Full text

, , +14