Direct demonstration of insulin-like growth factor-I-induced nitric oxide production by endothelial cells

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

Richard Palmer, Anthony G. Ferrige, Salvador Moncada · Nature · 1987 · 10.8K citations

Veterinary Medicine, Cell Biology, Physiology +10

Vascular endothelial cells synthesize nitric oxide from L-arginine

Richard Palmer, D. Ashton, Salvador Moncada · Nature · 1988 · 4.8K citations

Life Sciences, Cell Biology, Cell Signaling +4

Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells.

Marek W. Radomski, Richard Palmer, Salvador Moncada · Proceedings of the National Academy of Sciences · 1990 · 1.1K citations

Life Sciences, Biochemistry, Pharmacology +14

Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum

Katsuei Shibuki, Daisuke Okada · Nature · 1991 · 874 citations

Life Sciences, Neurobiology, Neuroscience +12

Molecular cloning and expression of a cDNA encoding endothelial cell nitric oxide synthase.

William C. Sessa, Jeffrey K. Harrison, Cynthia M. Barber et al. · Journal of Biological Chemistry · 1992 · 468 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13