CYSTOMETRIC EVALUATION OF BLADDER FUNCTION IN NON-ANESTHETIZED MICE WITH AND WITHOUT BLADDER OUTLET OBSTRUCTION

Abstract

Continuous cystometry can be reproducibly performed in awake, freely moving non-obstructed mice and mice with bladder outflow obstruction. The changes induced by infravesical obstruction in mice were similar to those previously found in rats. This model may be useful for investigations of genetically modified mice.