<b>Osmotic Demyelination Syndrome in End-Stage Renal Disease After Recent Hemodialysis:</b> MRI of the Brain

Abstract

In patients who develop osmotic demyelination syndrome after hemodialysis, the lesions may involve the pons or the pons and extrapontine sites. Most lesions that were followed up resolved rapidly and almost completely, favoring transient edema rather than demyelination. Blood chemistries suggested underlying changes in osmolality, particularly as a result of urea shift from the extracellular fluid.