Tunable coordination of a troposphosphite for fine-tuning of the Rh catalyzed asymmetric addition of phenylboronic acid to cyclohexenone

Abstract

Using the deoxycholic acid derived tropos biphenylphosphite as a Rh(i) chiral ligand different complexes are obtained, depending on the Rh : L molar ratio, that give rise to the formation of different chiral products in the asymmetric addition of phenylboronic acid to cyclohexenone.