Concepedia

Publication | Open Access

Deficiency of Interleukin-1 Receptor Antagonist Promotes Neointimal Formation After Injury

DOIFull Paper Access

107

Citations

11

References

2003

Year

Kikuo Isoda, Masaru Shiigai, Norio Ishigami, Taizo Matsuki, Reiko Horai, Ken-ichirou Nishikawa, Masatoshi Kusuhara, Yasuhiro Nishida, Yoichiro Iwakura, Fumitaka Ohsuzu
Circulation

Abstract

The absence of IL-1Ra promotes neointimal formation in mice after injury. These results suggest that endogenous IL-1Ra may suppress other occlusive vascular responses to injury, such as atherosclerosis and restenosis after angioplasty.

References

YearCitations

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