Concepedia

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Hemodynamic profiles of prostaglandin E1, isoproterenol, prostacyclin, and nifedipine in experimental porcine pulmonary hypertension

DOI

44

Citations

0

References

1991

Year

Richard C. Prielipp, Richard G. McLean, Myer H. Rosenthal, Ronald G. Pearl
Critical Care Medicine

Abstract

Vasodilators demonstrate unique hemodynamic drug profiles. Isoproterenol infusion is characterized by tachycardia and arrhythmias. Both PGE1 and PGI2 effectively decrease PAP and PVR. Nifedipine depressed Qt significantly in this glass-bead embolization model of acute pulmonary hypertension.