Increase of Intracellular Ca<sup>2+</sup>by Purinergic Receptors in Cultured Rat Lacrimal Gland Myoepithelial Cells

Kaori Ohtomo, Marie A. Shatos, Joanna Vrouvlianis, Dayu Li, Robin R. Hodges, Darlene A. Dartt

Investigative Ophthalmology & Visual Science · 2011 · 37 citations · 32 references

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Abstract

MECs can be isolated from rat lacrimal glands, and they express P2X(7), P2Y(1), P2Y(11), and P2Y(13) purinergic receptors. Surprisingly, BzATP binds the P2Y(1) receptor, which is primarily responsible for the BzATP-stimulated increase in [Ca(2+)](i).

References

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