Antidepressant-like Profile and Reduced Sensitivity to Rolipram in Mice Deficient in the PDE4D Phosphodiesterase Enzyme

The tail suspension test: A new method for screening antidepressants in mice

Lucien Stéru, R Chermat, Bernard Thierry et al. · Psychopharmacology · 1985 · 3.5K citations

Medicine, Pharmacology, Behavioral Pharmacology +11

Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus

Masashi Nibuya, EJ Nestler, R. S. Duman · Journal of Neuroscience · 1996 · 1.2K citations · Full text

Life Sciences, Neuroscience, Pharmacology +15

Serotonergic mediation of the effects of fluoxetine, but not desipramine, in the rat forced swimming test

M.E. Page, Michael J. Detke, A. Dalvi et al. · Psychopharmacology · 1999 · 383 citations

Medicine, Neuroscience, Pharmacology +12

Covariation of Activity in Habenula and Dorsal Raphé Nuclei Following Tryptophan Depletion

J. S. Morris, Katharine Smith, Philip J. Cowen et al. · NeuroImage · 1999 · 286 citations · Full text

Life Sciences, Neurobiology, Neuroscience +8

Impaired growth and fertility of cAMP-specific phosphodiesterase PDE4D-deficient mice

S.-L. Catherine Jin, François J. Richard, Wie-Peng Kuo et al. · Proceedings of the National Academy of Sciences · 1999 · 233 citations

Life Sciences, Cell Biology, Molecular Biology +13