Recognition of 2-aminothiazole-4-acetic acid derivatives by the peptide transporters PEPT1 and PEPT2

Molecular Similarity Indices in a Comparative Analysis (CoMSIA) of Drug Molecules to Correlate and Predict Their Biological Activity

G. Klebe, Ute Abraham, Thomas Mietzner · Journal of Medicinal Chemistry · 1994 · 1.8K citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Three-Dimensional Quantitative Structure−Activity Relationship Analyses Using Comparative Molecular Field Analysis and Comparative Molecular Similarity Indices Analysis To Elucidate Selectivity Differences of Inhibitors Binding to Trypsin, Thrombin, and Factor Xa

Markus Böhm, Jörg Stürzebecher, G. Klebe · Journal of Medicinal Chemistry · 1999 · 441 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Transport of Valganciclovir, a Ganciclovir Prodrug, via Peptide Transporters PEPT1 and PEPT2

Mitsuru Sugawara, Wei Huang, You‐Jun Fei et al. · Journal of Pharmaceutical Sciences · 2000 · 312 citations

Pharmacy, Pharmacokinetics, Pharmacology +10

Valacyclovir: A Substrate for the Intestinal and Renal Peptide Transporters PEPT1 and PEPT2

Malliga E. Ganapathy, Wei Huang, Hong Wang et al. · Biochemical and Biophysical Research Communications · 1998 · 295 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +10

Delta-aminolevulinic acid transport by intestinal and renal peptide transporters and its physiological and clinical implications.

Frank Döring, Justin D. Walter, Jutta Will et al. · Journal of Clinical Investigation · 1998 · 272 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17