Management of Acute Undifferentiated Agitation in the Emergency Department: A Randomized Double‐Blind Trial of Droperidol, Ziprasidone, and Midazolam

Abstract

Acutely agitated ED patients sedated with droperidol or ziprasidone required rescue medications to achieve adequate sedation less frequently than those sedated with midazolam. The onset of adequate sedation is delayed with ziprasidone, relative to the other agents.