The D-1 dopamine receptor antagonist SCH 23390 also interacts potently with brain serotonin (5-HT2) receptors

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

J E Leysen, C. J. E. Niemegeers, Jan M. Van Nueten et al. · Molecular Pharmacology · 1982 · 1.1K citations

Medicine, Medicinal Chemistry, Pharmacology +17

SCH 23390, a potential benzazepine antipsychotic with unique interactions on dopaminergic systems.

Louis C. Iorio, A Barnett, Frederick H. Leitz et al. · Journal of Pharmacology and Experimental Therapeutics · 1983 · 897 citations

Medicine, Pharmacology, Psychiatry +15

Pharmacological effects of a specific dopamine D-1 antagonist SCH 23390 in comparison with neuroleptics

A. V. Christensen, J. Arnt, John Hyttel et al. · Life Sciences · 1984 · 376 citations

Medicine, Neuroscience, Pharmacology +12

5HT-receptor antagonist properties of SCH 23390 in vascular smooth muscle and brain

Peter E. Hicks, Hans E. Schoemaker, Salomón Z. Langer · European Journal of Pharmacology · 1984 · 105 citations

Medicine, Neuroscience, Pharmacology +11

Correlations between different measures of antiserotonin activity of drugs

R. Ortmann, Serge Bischoff, E. Radeke et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 1982 · 99 citations

Medicine, Pharmacology, Pharmacodynamics +1