Imidazole antimycotics affect the activity of various ion channels and insulin secretion in mouse pancreatic B-cells

Depletion of intracellular calcium stores activates a calcium current in mast cells

Markus Hoth, Reinhold Penner · Nature · 1992 · 1.7K citations

Life Sciences, Cell Biology, Physiology +13

Inhibition of Ca(2+)-dependent K+ transport and cell dehydration in sickle erythrocytes by clotrimazole and other imidazole derivatives.

Carlo Brugnara, Lucia De Franceschi, Seth L. Alper · Journal of Clinical Investigation · 1993 · 364 citations · Full text

Life Sciences, Pharmacology, Physiology +17

High affinity inhibition of Ca(2+)-dependent K+ channels by cytochrome P-450 inhibitors.

Javier Álvarez, Mayte Montero, Javier Garcı́a-Sancho · Journal of Biological Chemistry · 1992 · 279 citations · Full text

Medicine, Pharmacology, Biochemical Pharmacology +9

Therapy with oral clotrimazole induces inhibition of the Gardos channel and reduction of erythrocyte dehydration in patients with sickle cell disease.

Carlo Brugnara, Benjamin Gee, C. C. Armsby et al. · Journal of Clinical Investigation · 1996 · 240 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Properties and calcium‐dependent inactivation of calcium currents in cultured mouse pancreatic B‐cells.

Timothy Plant · The Journal of Physiology · 1988 · 180 citations

Life Sciences, Cell Biology, Physiology +15