Concepedia

Activation by IL-1 of bovine articular chondrocytes in culture within a 3D collagen-based scaffold. An in vitro model to address the effect of compounds with therapeutic potential in osteoarthritis

D. Cortial, Jérôme Gouttenoire, Cécile F. Rousseau, M.-C. Ronzière, Nathalie Piccardi, Philippe Msika, D. Herbage, Frédéric Mallein‐Gérin, A.M. Freyria

Osteoarthritis and Cartilage · 2006 · 62 citations · 41 references

Open access

Concepts

EngineeringBioengineeringOrthopaedic SurgeryCartilage RepairInflammationTissue EngineeringCartilage BiologyCartilage MetabolismCartilage RegenerationCartilage Tissue EngineeringCollagen-based BiomaterialsOsteoarthritisCartilage Tissue Engineering ScaffoldsChondrocyte CultureChondrogenic ScaffoldsImmunomodulation In Cartilage RegenerationInflammatory Mediators In CartilageOsteoarthritis Cartilage

References

41

Treatment of Deep Cartilage Defects in the Knee with Autologous Chondrocyte Transplantation

Mats Brittberg, Anders Lindahl, Anders Nilsson et al. · New England Journal of Medicine · 1994 · 5.5K citations · Full text

Medicine, Orthopaedic Surgery, Orthopedic Surgery +14

Scaffolds in tissue engineering bone and cartilage

Dietmar W. Hutmacher · Biomaterials · 2000 · 4.9K citations

Engineering, Bioengineering, Biomedical Engineering +12

Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

S.S. Glasson, Roger Askew, Barbara Sheppard et al. · Nature · 2005 · 1.3K citations

Dentistry, Genetics, Molecular Genetics +14

ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro

Heather Stanton, Fraser M. Rogerson, Charlotte J. East et al. · Nature · 2005 · 915 citations

Medicine, Molecular Biology, Orthopaedic Surgery +14

Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage

Jeremy Saklatvala · Nature · 1986 · 745 citations · Full text

Medicine, Immunology, Orthopaedic Surgery +14