Recombinant Human VEGF₁₆₅b Inhibits Experimental Choroidal Neovascularization

Abstract

These results show that VEGF-A(165)b is a potent antiangiogenic agent in a mouse model of age-related macular degeneration and suggest that increasing the ratio of antiangiogenic-to-proangiogenic isoforms may be therapeutically effective in this condition.