miR‐141 modulates androgen receptor transcriptional activity in human prostate cancer cells through targeting the small heterodimer partner protein

Abstract

Shp is a target for miR-141 and it is downregulated in cultured human PCa cells with the involvement of upregulation of miR-141, which promotes AR transcriptional activity. Moreover, Shp and miR-141 could be targets for chemoprevention for PCa.