<i>In Vitro</i> Observations on the Influence of Copper Peptide Aids for the LED Photoirradiation of Fibroblast Collagen Synthesis

Abstract

LED-PI maintained human fibroblast (HS68) viability and increased collagen synthesis when applied by itself. In the combinative stimulation for in vitro collagen production (when LED-PI was followed by Cu-GHK-supplied incubation), stimulated cells showed increased bFGF secretion, P1CP production, and COL1 expression, compared to the LED-PI treatment alone.