Arylations of Substituted Enamides by Aryl Iodides: Regio- and Stereoselective Synthesis of (<i>Z</i>)-β-Amido-β-Arylacrylates

Abstract

Arylations of substituted enamides by aryl iodides were achieved for the first time via an unusual PdCl2(COD)/Ag3PO4 catalytic system. A broad range of (Z)-β-amido-β-arylacrylates were prepared regio- and stereoselectively in a highly efficient manner.