Concepedia

Insights into designing the dual-targeted HER2/HSP90 inhibitors

Chien‐Yu Chen, Calvin Yu‐Chian Chen

Journal of Molecular Graphics and Modelling · 2010 · 66 citations · 22 references

DOI

Concepts

References

22

Clinical evaluation of ZD6474, an orally active inhibitor of VEGF and EGF receptor signaling, in patients with solid, malignant tumors

Scott N. Holden, Sabine Eckhardt, R. Basser et al. · Annals of Oncology · 2005 · 306 citations · Full text

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Multi-Target-Directed Drug Design Strategy: From a Dual Binding Site Acetylcholinesterase Inhibitor to a Trifunctional Compound against Alzheimer’s Disease

María Laura Bolognesi, Andrea Cavalli, Luca Valgimigli et al. · Journal of Medicinal Chemistry · 2007 · 258 citations · Full text

, , +17

Down-regulation of Myeloid Cell Leukemia-1 through Inhibiting Erk/Pin 1 Pathway by Sorafenib Facilitates Chemosensitization in Breast Cancer

Qingqing Ding, Longfei Huo, Jer-Yen Yang et al. · Cancer Research · 2008 · 194 citations

, , +17

Evaluation of 8-Arylsulfanyl, 8-Arylsulfoxyl, and 8-Arylsulfonyl Adenine Derivatives as Inhibitors of the Heat Shock Protein 90

Laura Llauger, Huazhong He, Joungnam Kim et al. · Journal of Medicinal Chemistry · 2005 · 192 citations · Full text

, , +11

Identification of Potent Water Soluble Purine-Scaffold Inhibitors of the Heat Shock Protein 90

Huazhong He, Danuta Zatorska, Joungnam Kim et al. · Journal of Medicinal Chemistry · 2005 · 178 citations · Full text

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