Chromosomal location of the human tumor necrosis factor receptor genes

Abstract

TNFR1 and TNFR2, the genes encoding the two forms of the human tumor necrosis factor receptor, were localized to normal human chromosomes by in situ hybridization and Southern blot analysis of a series of human × mouse hybrid cell lines. TNFR1 maps to 12p13 and TNFR2 maps to 1p36.