Optimal Lesion Assessment Following Acute Radio Frequency Ablation of Porcine Kidney: Cellular Viability or Histopathology?

Abstract

While RFA produces discernible histological changes acutely on H & E, these alterations are variable and patchy, and they alternate with areas of well preserved tissue. Therefore, NADH staining should always be used to assess and verify cellular death in RFA lesions. In this study no skip areas of viable cells were noted within areas of ablated tissue on NADH staining.