Incorporation of C14-Acetate into Intestinal Fatty Acids of Rats with Cannulated Bile Ducts.

Abstract

Summary1. Deprivation of bile flow to the rat intestine by means of cannulation of the bile duct did not affect the ability of the intestine to accumulate normal amounts of highly labeled fatty acids after administration of C14-acetate as shown by comparison with sham-operated, pair-fed controls. 2. Total radioactivity in the biliary fatty acids amounted to only 5-16% of the amount found in the intestinal fatty acids in the time periods studied. 3. Fatty acids of combined intestinal and cecal contents of cannulated animals contained more fatty acid but of a lower specific activity than those of control rats.