Publication | Closed Access
B<sub>12</sub>‐<i>retro</i>‐Riboswitches: Constitutional Switching of B<sub>12</sub> Coenzymes Induced by Nucleotides
25
Citations
22
References
2005
Year
ChromatinNucleic Acid ChemistryTemperature DependentBiochemistryNatural SciencesGeneticsMolecular BiologyConstitutional SwitchingB12 ConjugateMolecular GeneticsConstitutional SwitchVitamin B ComplexMedicineEpigeneticsRna ProcessingProtein Synthesis
A vitamin that switches states: The appended nucleotide base B assists in the constitutional switch from the base-on form of the B12 conjugate (blue, with a coordinated 5,6-dimethylbenzimidazole (DMB) unit) to the base-off form (red, with a free DMB unit). The process is strongly temperature dependent.
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