Tandem Sequential Ring‐Closing Metathesis/Diels–Alder/Cross‐Metathesis: Formation of Polycyclic Compounds by a New Three‐Component Reaction

Abstract

Abstract Polycyclic oxygenated compounds have been generated from penta‐ or hexadienyl propargyl ethers by a new procedure that combines the selective formation of a 1,3‐diene by ring‐closing metathesis (RCM), a Diels–Alder (DA) reaction and subsequent cross‐metathesis (CM) with a chosen alkene, which allows the functionalization of the vinyl group generated during the first step. All these processes can be performed in a one‐pot reaction with a yield of up to 63 %. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)