Functional characterization of transcription factor binding sites for HNF1-alpha, HNF3-beta (FOXA2), HNF4-alpha, Sp1 and Sp3 in the human prothrombin gene enhancer

A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis

SR Poort, FR Rosendaal, PH Reitsma et al. · Blood · 1996 · 3.1K citations · Full text

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Matlnd and Matlnspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data

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Growth of human hepatoma cells lines with differentiated functions in chemically defined medium.

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TRANSFAC: an integrated system for gene expression regulation

Edgar Wingender · Nucleic Acids Research · 2000 · 1.3K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

Opening of Compacted Chromatin by Early Developmental Transcription Factors HNF3 (FoxA) and GATA-4

Lisa Ann Cirillo, Frank R. Lin, Isabel Cuesta et al. · Molecular Cell · 2002 · 1.2K citations · Full text

Life Sciences, Genetics, Molecular Biology +14