Helvetica Chimica Acta · 1954 · 72 citations · 7 references
PharmacyMedicinal ChemistryPharmacologyDrug DiscoveryNeuropharmacologySynthetic Medicinal ChemistryMedicinal PlantsNatural Product DerivatizationPlant Alkaloids
Abstract Reserpine, C 33 H 40 O 9 N 2 , has been isolated from Rauwolfia serpentina Benth . Reserpine is an ester alkaloid yielding reserpic acid, 3,4,5‐trimethoxybenzoic acid and methanol on hydrolysis. Degradation products of reserpic acid make it likely that reserpic acid is a yohimbane derivate, and a hypothetical structure for reserpine has been put forward which is in agreement with the facts known so far.
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Biogenesis of the Strychnos Alkaloids
R. B. Woodward · Nature · 1948 · 107 citations
On the constitution of reserpine
A. Furlenmeier, Robert Lucas, H. B. MacPhillamy et al. · Cellular and Molecular Life Sciences · 1953 · 32 citations