Sugar Calixarenes: Preparation of Calix[4]arenes Substituted at the Lower and Upper Rims with <i>O</i>‐Glycosyl Groups

Abstract

A chiral hydrophilic environment is created at either rim of calix[4]arene by the synthesis of glycosyl derivatives such as the water-soluble tetragalactosyl calixarene 1. This derivative is potentially an attractive synthetic receptor for chiral recognition of polar organic molecules.