Hypercapnia Accelerates Wound Healing in Endothelial Cell Monolayers Exposed to Hypoxia

Abstract

These results suggest that hypercapnia, rather than acidosis per se, accelerated the wound healing in HUVEC monolayers cultured under hypoxic conditions. The effect of hypercapnia on wound healing was due, at least in part, to the stimulation of cell proliferation by hypercapnia.