Evidence for Synergy Between α ₂ -Adrenergic and Nonadrenergic Mechanisms in Central Blood Pressure Regulation

Abstract

These results demonstrate that a central imidazoline-sensitive, but non--alpha(2)-adrenergic, mechanism can modify BP by itself. This mechanism, which may involve I(1)BS, interacts synergistically with an alpha(2)-adrenergic mechanism to decrease BP.