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Blockade of Tau Hyperphosphorylation and Aβ1–42 Generation by the Aminotetrahydrofuran Derivative ANAVEX2-73, a Mixed Muscarinic and σ1 Receptor Agonist, in a Nontransgenic Mouse Model of Alzheimer’s Disease

Valentine Lahmy, Johann Meunier, Susanna Malmström, Gaëlle Naert, Laurent Givalois, Seung Hyun Kim, Vanessa Villard, A Vamvakidès, Tangui Maurice

Neuropsychopharmacology · 2013 · 152 citations · 72 references

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72

Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival

Teruo Hayashi, Tsung‐Ping Su · Cell · 2007 · 1.8K citations · Full text

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Release of Alzheimer Amyloid Precursor Derivatives Stimulated by Activation of Muscarinic Acetylcholine Receptors

Roger M. Nitsch, Barbara E. Slack, Richard J. Wurtman et al. · Science · 1992 · 899 citations

, , +17

Decreased nuclear β‐catenin, tau hyperphosphorylation and neurodegeneration in GSK‐3β conditional transgenic mice

José J. Lucas · The EMBO Journal · 2001 · 898 citations · Full text

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LTP Inhibits LTD in the Hippocampus via Regulation of GSK3β

Stéphane Peineau, Changiz Taghibiglou, Clarrisa A. Bradley et al. · Neuron · 2007 · 689 citations · Full text

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Effects of Xanomeline, a Selective Muscarinic Receptor Agonist, on Cognitive Function and Behavioral Symptoms in Alzheimer Disease

N. Bodick, Walter Offen, Allan I. Levey et al. · Archives of Neurology · 1997 · 685 citations

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