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Ligament Replacement with an Absorbable Copolymer Carbon Fiber Scaffold-Early Clinical Experience
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1985
Year
Tissue EngineeringEngineeringSurgeryBiomedical EngineeringOrthopaedic SurgeryAnterior Cruciate LigamentRegenerative MedicineSoft Tissue InjuryOsteoarthritisOrthopaedicsArthroscopic TechniqueJoint ReplacementLigament ReplacementKnee Ligament InstabilitiesTissue ScaffoldReconstructive SurgeryWound HealingMusculoskeletal SurgerySoft Tissue ReconstructionMedicinePlastic Surgery
Eighty-two patients, average age 29 years, were surgically treated (during the period from April 1981 to July 1983) for both acute (8%) and chronic (92%) knee ligament instabilities. An absorbable copolymer-carbon fiber ligament prosthesis was used as a tissue scaffold. Seventy-five percent had anterior cruciate ligament reconstructions, 6% had anterior cruciate and posterior cruciate ligament reconstructions, 6% had just posterior cruciate ligament reconstructions, and 9% had other combinations of anterior cruciate ligament, medical collateral ligament, and lateral collateral ligament reconstructions. Preoperative and postoperative evaluation, consisting of questionnaires, physical examinations, and isoskinetic testing, revealed significant improvements in categories of stability, pain, function, and strength persisting to the end of the study at 24 months. Arthroscopic examination and histologic studies of retrieved specimens demonstrated well-vascularized reconstructions with collagenous tissue ingrowth into the carbon-copolymer implants.