Publication | Closed Access
Observations on a New Example of the A<sub>m</sub> Phenotype which Demonstrates Reduced A Secretion
16
Citations
16
References
1973
Year
HistocompatibilityImmunohematologyLaboratory ImmunologyGeneticsRed CellsImmunologyImmune RegulationPathologyHumoral ResponseMolecular GeneticsImmune SystemImmunogeneticsY Y GenesMolecular DiagnosticsVariant InterpretationGenetic PredispositionAutoimmune DiseaseNew ExampleAutoimmunityHumoral ImmunityGenetic VariationImmune FunctionAntibody BiologyBiologyGenetic DisorderNatural SciencesEvolutionary BiologyPathogenesisMedicineA M Phenotype
Abstract. A new example of the A m phenotype is described. The red cells have a very weak A status, best demonstrated by ‘immune’ anti‐A sera using enzyme techniques. The serum contains normal anti‐B but no anti‐A or A substance. The saliva contains A, H and Le a substances, but the A:H substance ratio was lower than normal, indicating that the y y genes reduce the formation of secreted A as well as that of cellular A substance.
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