INTRAGRAFT ACTIVATION OF GENES ENCODING CYTOTOXIC T LYMPHOCYTE EFFECTOR MOLECULES PRECEDES THE HISTOLOGICAL EVIDENCE OF REJECTION IN HUMAN CARDIAC TRANSPLANTATION1

Abstract

The assessment of intragraft levels of cytotoxic T lymphocyte effector molecule mRNA represents a valuable tool in the monitoring of cardiac allograft rejection, especially considering the predictive value for warning of impending acute rejection.