Antidiabetic Activity Of <i>Cassia auriculata</i> Seeds In Alloxan Induced Diabetic Rats

SS Jalalpure, M. B. Patil, Aruna Pai, Mohammed Salahuddin

Nigerian Journal of Natural Products and Medicine · 2005 · 16 citations · 0 references

Concepts

Abstract

The petroleum ether (40-60 ºC), chloroform, ethyl acetate, ethanol and aqueous extracts of Cassia auriculata seeds, obtained by soxhlet extraction method were evaluated for antidiabetic activity using alloxan (60 mg/kg through tail vein) induced hypoglycemic rats on acute and prolonged treatment. The potency of extracts was compared with that of standard tolbutamide (250 mg/kg body weight, p.o.). Petroleum ether and ethyl acetate extracts showed highly significant (p