Nigerian Journal of Natural Products and Medicine · 2005 · 16 citations · 0 references
Cassia AuriculataMedicineHerbal MedicineDiabetesPhysiologyAntidiabetic ActivityStandard TolbutamidePhytopharmacologyPetroleum EtherPhytochemicalDiabetes MellitusTail VeinPhytochemistryPharmacology
The petroleum ether (40-60 ºC), chloroform, ethyl acetate, ethanol and aqueous extracts of Cassia auriculata seeds, obtained by soxhlet extraction method were evaluated for antidiabetic activity using alloxan (60 mg/kg through tail vein) induced hypoglycemic rats on acute and prolonged treatment. The potency of extracts was compared with that of standard tolbutamide (250 mg/kg body weight, p.o.). Petroleum ether and ethyl acetate extracts showed highly significant (p